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The Intracellular Trafficking Pathway of Transferrin

BACKGROUND: Transferrin (Tf) is an iron-binding protein that facilitates iron-uptake in cells. Iron-loaded Tf first binds to the Tf receptor (TfR) and enters the cell through clathrin-mediated endocytosis. Inside the cell, Tf is trafficked to early endosomes, delivers iron, and then is subsequently...

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Hlavní autoři: Mayle, Kristine M., Le, Alexander M., Kamei, Daniel T.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3288267/
https://ncbi.nlm.nih.gov/pubmed/21968002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2011.09.009
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