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The Intracellular Trafficking Pathway of Transferrin
BACKGROUND: Transferrin (Tf) is an iron-binding protein that facilitates iron-uptake in cells. Iron-loaded Tf first binds to the Tf receptor (TfR) and enters the cell through clathrin-mediated endocytosis. Inside the cell, Tf is trafficked to early endosomes, delivers iron, and then is subsequently...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3288267/ https://ncbi.nlm.nih.gov/pubmed/21968002 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2011.09.009 |
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