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Prototypic chromatin insulator cHS4 protects retroviral transgene from silencing in Schistosoma mansoni

Vesicular stomatitis virus glycoprotein (VSVG) pseudotyped murine leukemia virus (MLV) virions can transduce schistosomes, leading to chromosomal integration of reporter transgenes. To develop VSVG-MLV for functional genomics in schistosomes, the influence of the chicken β-globin cHS4 element, a pro...

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Autors principals: Suttiprapa, Sutas, Rinaldi, Gabriel, Brindley, Paul J.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3288229/
https://ncbi.nlm.nih.gov/pubmed/21918820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11248-011-9556-0
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