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Determination of the Distance between the Mo(V) and Fe(III) Heme Centers of Wild Type Human Sulfite Oxidase by Pulsed EPR Spectroscopy

Intramolecular electron transfer (IET) between the molybdenum and heme centers of vertebrate sulfite oxidase (SO) is proposed to be a key step in the catalytic cycle of the enzyme. However, the X-ray crystallographic distance between these centers, R(MoFe) = 32.3 Å, appears to be too long for the ra...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Astashkin, Andrei V., Rajapakshe, Asha, Cornelison, Matthew, Johnson-Winters, Kayunta, Enemark, John H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3288158/
https://ncbi.nlm.nih.gov/pubmed/22229742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp210578f
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