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Motion and Flexibility in Human Cytochrome P450 Aromatase

The crystal structures of human placental aromatase in complex with the substrate androstenedione and exemestane have revealed an androgen-specific active site and the structural basis for higher order organization. However, X-ray structures do not provide accounts of movements due to short-range fl...

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Autori principali: Jiang, Wenhua, Ghosh, Debashis
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3288111/
https://ncbi.nlm.nih.gov/pubmed/22384274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032565
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