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Hemokinin-1 Gene Expression Is Upregulated in Microglia Activated by Lipopolysaccharide through NF-κB and p38 MAPK Signaling Pathways

The mammalian tachykinins, substance P (SP) and hemokinin-1 (HK-1), are widely distributed throughout the nervous system and/or peripheral organs, and function as neurotransmitters or chemical modulators by activating their cognate receptor NK(1). The TAC1 gene encoding SP is highly expressed in the...

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Detalhes bibliográficos
Main Authors: Sakai, Atsushi, Takasu, Kumiko, Sawada, Makoto, Suzuki, Hidenori
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3288086/
https://ncbi.nlm.nih.gov/pubmed/22384199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032268
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