Brain Deletion of Insulin Receptor Substrate 2 Disrupts Hippocampal Synaptic Plasticity and Metaplasticity

OBJECTIVE: Diabetes mellitus is associated with cognitive deficits and an increased risk of dementia, particularly in the elderly. These deficits and the corresponding neurophysiological structural and functional alterations are linked to both metabolic and vascular changes, related to chronic hyper...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Costello, Derek A., Claret, Marc, Al-Qassab, Hind, Plattner, Florian, Irvine, Elaine E., Choudhury, Agharul I., Giese, K. Peter, Withers, Dominic J., Pedarzani, Paola
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2012
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3287998/
https://ncbi.nlm.nih.gov/pubmed/22383997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031124
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