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Addition of multiple rare SNPs to known common variants improves the association between disease and gene in the Genetic Analysis Workshop 17 data

The upcoming release of new whole-genome genotyping technologies will shed new light on whether there is an associative effect of previously immeasurable rare variants on incidence of disease. For Genetic Analysis Workshop 17, our team focused on a statistical method to detect associations between g...

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Main Authors: Sykes, Jenna, Cheng, Lu, Xu, Wei, Tsao, Ming-Sound, Liu, Geoffrey, Pintilie, Melania
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3287939/
https://ncbi.nlm.nih.gov/pubmed/22373301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1753-6561-5-S9-S97
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