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Association tests for rare and common variants based on genotypic and phenotypic measures of similarity between individuals

Genome-wide association studies have helped us identify thousands of common variants associated with several widespread complex diseases. However, for most traits, these variants account for only a small fraction of phenotypic variance or heritability. Next-generation sequencing technologies are bei...

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Autori principali: Thalamuthu, Anbupalam, Zhao, Jingyuan, Keong, Garrett Teoh Hor, Kondragunta, Venkateswarlu, Mukhopadhyay, Indranil
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3287930/
https://ncbi.nlm.nih.gov/pubmed/22373048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1753-6561-5-S9-S89
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