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Enriching rare variants using family-specific linkage information

Genome-wide association studies have been successful in identifying common variants for common complex traits in recent years. However, common variants have generally failed to explain substantial proportions of the trait heritabilities. Rare variants, structural variations, and gene-gene and gene-e...

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Hlavní autoři: Shi, Gang, Simino, Jeannette, Rao, Dabeeru C
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3287923/
https://ncbi.nlm.nih.gov/pubmed/22373363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1753-6561-5-S9-S82
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