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Strategies for selection of subjects for sequencing after detection of a linkage peak

Linkage analysis has the potential to localize disease genes of interest, but the choice of which subjects to select for follow-up sequencing after identifying a linkage peak might influence the ability to find a disease gene. We compare nine different strategies for selection of subjects for follow...

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Hlavní autoři: Allen-Brady, Kristina, Farnham, James, Cannon-Albright, Lisa
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3287917/
https://ncbi.nlm.nih.gov/pubmed/22373232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1753-6561-5-S9-S77
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