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Shared genomic segment analysis. Mapping disease predisposition genes in extended pedigrees using SNP genotype assays

We examine the utility of high density genotype assays for predisposition gene localization using extended pedigrees. Results for the distribution of the number and length of genomic segments shared identical by descent among relatives previously derived in the context of genomic mismatch scanning a...

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Detalhes bibliográficos
Main Authors: Thomas, Alun, Camp, Nicola J, Farnham, James M, Allen-Brady, Kristina, Cannon-Albright, Lisa A
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964273/
https://ncbi.nlm.nih.gov/pubmed/18093282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-1809.2007.00406.x
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