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Integrating binary traits with quantitative phenotypes for association mapping of multivariate phenotypes

Clinical binary end-point traits are often governed by quantitative precursors. Hence it may be a prudent strategy to analyze a clinical end-point trait by considering a multivariate phenotype vector, possibly including both quantitative and qualitative phenotypes. A major statistical challenge lies...

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Bibliographic Details
Main Authors: Mukhopadhyay, Indranil, Saha, Sujayam, Ghosh, Saurabh
Format: Artigo
Language:Inglês
Published: BioMed Central 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3287913/
https://ncbi.nlm.nih.gov/pubmed/22373144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1753-6561-5-S9-S73
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