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Identifying variants that contribute to linkage for dichotomous and quantitative traits in extended pedigrees

Compared to genome-wide association analysis, linkage analysis is less influenced by allelic heterogeneity. The use of linkage information in large families should provide a great opportunity to identify less frequent variants. We perform a linkage scan for both dichotomous and quantitative traits i...

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Sonraí Bibleagrafaíochta
Main Authors: Chen, Wei-Min, Manichaikul, Ani, Rich, Stephen S
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2011
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3287907/
https://ncbi.nlm.nih.gov/pubmed/22373516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1753-6561-5-S9-S68
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