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Comparison of scoring methods for the detection of causal genes with or without rare variants

Rare causal variants are believed to significantly contribute to the genetic basis of common diseases or quantitative traits. Appropriate statistical methods are required to discover the highest possible number of disease-relevant variants in a genome-wide screening study. The publicly available Gen...

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Detalhes bibliográficos
Main Authors: Scholz, Markus, Kirsten, Holger
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3287886/
https://ncbi.nlm.nih.gov/pubmed/22373454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1753-6561-5-S9-S49
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