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An aggregating U-Test for a genetic association study of quantitative traits
We propose a novel aggregating U-test for gene-based association analysis. The method considers both rare and common variants. It adaptively searches for potential disease-susceptibility rare variants and collapses them into a single “supervariant.” A forward U-test is then used to assess the joint...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3287858/ https://ncbi.nlm.nih.gov/pubmed/22373246 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1753-6561-5-S9-S23 |
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