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Gene-based partial least-squares approaches for detecting rare variant associations with complex traits

Genome-wide association studies are largely based on single-nucleotide polymorphisms and rest on the common disease/common variants (single-nucleotide polymorphisms) hypothesis. However, it has been argued in the last few years and is well accepted now that rare variants are valuable for studying co...

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Detalhes bibliográficos
Main Authors: Turkmen, Asuman S, Lin, Shili
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3287853/
https://ncbi.nlm.nih.gov/pubmed/22373126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1753-6561-5-S9-S19
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