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Identification of genes associated with complex traits by testing the genetic dissimilarity between individuals
Using the exome sequencing data from 697 unrelated individuals and their simulated disease phenotypes from Genetic Analysis Workshop 17, we develop and apply a gene-based method to identify the relationship between a gene with multiple rare genetic variants and a phenotype. The method is based on th...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3287845/ https://ncbi.nlm.nih.gov/pubmed/22373401 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1753-6561-5-S9-S120 |
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