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Identification of epistatic effects using a protein–protein interaction database

Epistasis (i.e. gene–gene interaction) has long been recognized as an important mechanism underlying the complexity of the genetic architecture of human traits. Definitions of epistasis range from the purely molecular to the traditional statistical measures of interaction. The statistical detection...

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Detalhes bibliográficos
Main Authors: Sun, Yan V., Kardia, Sharon L.R.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2957319/
https://ncbi.nlm.nih.gov/pubmed/20736252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddq356
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