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Optimal study design for pioglitazone in septic pediatric patients
The objective was to demonstrate the methodology and process of optimal sparse sampling pharmacokinetics (PK). This utilized a single daily dose of pioglitazone for pediatric patients with severe sepsis and septic shock based upon adult and minimal adolescent data. Pioglitazone pharmacokinetics were...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3287370/ https://ncbi.nlm.nih.gov/pubmed/21667139 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10928-011-9202-8 |
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