Efficacy Results of a Trial of a Herpes Simplex Vaccine

BACKGROUND: Two previous studies of a herpes simplex virus type 2 (HSV-2) subunit vaccine containing glycoprotein D in HSV-discordant couples revealed 73% and 74% efficacy against genital disease in women who were negative for both HSV type 1 (HSV-1) and HSV-2 antibodies. Efficacy was not observed i...

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Main Authors: Belshe, Robert B., Leone, Peter A., Bernstein, David I., Wald, Anna, Levin, Myron J., Stapleton, Jack T., Gorfinkel, Iris, Morrow, Rhoda L. Ashley, Ewell, Marian G., Stokes-Riner, Abbie, Dubin, Gary, Heineman, Thomas C., Schulte, Joann M., Deal, Carolyn D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3287348/
https://ncbi.nlm.nih.gov/pubmed/22216840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1103151
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