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Correlate of Immune Protection Against HSV-1 Genital Disease in Vaccinated Women

Background. Previously we conducted a double-blind controlled, randomized efficacy field trial of gD-2 HSV vaccine adjuvanted with ASO4 in 8323 women. Subjects had been previously selected to be seronegative for HSV-1 and HSV-2. We found that vaccine was 82% protective against HSV-1 genital disease,...

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Detalhes bibliográficos
Main Authors: Belshe, Robert B., Heineman, Thomas C., Bernstein, David I., Bellamy, Abbie R., Ewell, Marian, van der Most, Robbert, Deal, Carolyn D.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3935479/
https://ncbi.nlm.nih.gov/pubmed/24285844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jit651
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