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An Unsuspected Property of Natriuretic Peptides: Promotion of Calcium-Dependent Catecholamine Release via Protein Kinase G-Mediated Phosphodiesterase Type 3 Inhibition

BACKGROUND: Although natriuretic peptides are considered cardioprotective, clinical heart failure trials with recombinant BNP (nesiritide) failed to prove it. Unsuspected proadrenergic effects might oppose the anticipated benefits of natriuretic peptides. METHODS AND RESULTS: We investigated whether...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Chan, Noel Yan-Ki, Seyedi, Nahid, Takano, Kenichi, Levi, Roberto
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3287346/
https://ncbi.nlm.nih.gov/pubmed/22158783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.111.059097
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