Cxcr2 and Cxcl5 regulate the IL-17/G-CSF axis and neutrophil homeostasis in mice

Neutrophils are essential for maintaining innate immune surveillance under normal conditions, but also represent a major contributor to tissue damage during inflammation. Neutrophil homeostasis is therefore tightly regulated. Cxcr2 plays a critical role in neutrophil homeostasis, as Cxcr2(–/–) mice...

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Autors principals: Mei, Junjie, Liu, Yuhong, Dai, Ning, Hoffmann, Christian, Hudock, Kristin M., Zhang, Peggy, Guttentag, Susan H., Kolls, Jay K., Oliver, Paula M., Bushman, Frederic D., Worthen, G. Scott
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3287232/
https://ncbi.nlm.nih.gov/pubmed/22326959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI60588
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