Cdc42 and Rab8a are critical for intestinal stem cell division, survival, and differentiation in mice

The constant self renewal and differentiation of adult intestinal stem cells maintains a functional intestinal mucosa for a lifetime. However, the molecular mechanisms that regulate intestinal stem cell division and epithelial homeostasis are largely undefined. We report here that the small GTPases...

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Hlavní autoři: Sakamori, Ryotaro, Das, Soumyashree, Yu, Shiyan, Feng, Shanshan, Stypulkowski, Ewa, Guan, Yinzheng, Douard, Veronique, Tang, Waixing, Ferraris, Ronaldo P., Harada, Akihiro, Brakebusch, Cord, Guo, Wei, Gao, Nan
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2012
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3287229/
https://ncbi.nlm.nih.gov/pubmed/22354172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI60282
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