Direct leptin action on POMC neurons regulates glucose homeostasis and hepatic insulin sensitivity in mice

Leptin action on its receptor (LEPR) stimulates energy expenditure and reduces food intake, thereby lowering body weight. One leptin-sensitive target cell mediating these effects on energy balance is the proopiomelano­cortin (POMC) neuron. Recent evidence suggests that the action of leptin on POMC n...

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Detalhes bibliográficos
Main Authors: Berglund, Eric D., Vianna, Claudia R., Donato, Jose, Kim, Mi Hwa, Chuang, Jen-Chieh, Lee, Charlotte E., Lauzon, Danielle A., Lin, Peagan, Brule, Laura J., Scott, Michael M., Coppari, Roberto, Elmquist, Joel K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3287225/
https://ncbi.nlm.nih.gov/pubmed/22326958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI59816
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