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Tissue-specific alternative polyadenylation at the imprinted gene Mest regulates allelic usage at Copg2

The gene Mest (also known as Peg1) is regulated by genomic imprinting in the mouse and only the paternal allele is active for transcription. MEST is similarly imprinted in humans, where it is a candidate for the growth retardation Silver-Russell syndrome. The MEST protein belongs to an ancient famil...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: MacIsaac, Julia L., Bogutz, Aaron B., Morrissy, A. Sorana, Lefebvre, Louis
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3287194/
https://ncbi.nlm.nih.gov/pubmed/22053079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr871
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