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Tissue-specific alternative polyadenylation at the imprinted gene Mest regulates allelic usage at Copg2

The gene Mest (also known as Peg1) is regulated by genomic imprinting in the mouse and only the paternal allele is active for transcription. MEST is similarly imprinted in humans, where it is a candidate for the growth retardation Silver-Russell syndrome. The MEST protein belongs to an ancient famil...

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Detalhes bibliográficos
Main Authors: MacIsaac, Julia L., Bogutz, Aaron B., Morrissy, A. Sorana, Lefebvre, Louis
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3287194/
https://ncbi.nlm.nih.gov/pubmed/22053079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr871
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