High tidal volume mechanical ventilation-induced lung injury in rats is greater after acid instillation than after sepsis-induced acute lung injury, but does not increase systemic inflammation: an experimental study

BACKGROUND: To examine whether acute lung injury from direct and indirect origins differ in susceptibility to ventilator-induced lung injury (VILI) and resultant systemic inflammatory responses. METHODS: Rats were challenged by acid instillation or 24 h of sepsis induced by cecal ligation and punctu...

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Detalhes bibliográficos
Main Authors: Kuiper, Jan Willem, Plötz, Frans B, Groeneveld, AB Johan, Haitsma, Jack J, Jothy, Serge, Vaschetto, Rosanna, Zhang, Haibo, Slutsky, Arthur S
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3287130/
https://ncbi.nlm.nih.gov/pubmed/22204611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2253-11-26
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