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The interplay of ubiquitous DNA-binding factors, availability of binding sites in the chromatin, and DNA methylation in the differential regulation of phosphoenolpyruvate carboxykinase gene expression.

We have identified DNA elements in the phosphoenolpyruvate carboxykinase (PEPCK) gene promoter which are bound 'in vivo' by proteins under conditions of basal level gene expression and have evaluated several hypothesis to account for the tissue specific expression of the gene. In vitro DNa...

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Bibliografische gegevens
Hoofdauteurs: Faber, S, Ip, T, Granner, D, Chalkley, R
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1991
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC328709/
https://ncbi.nlm.nih.gov/pubmed/1716357
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