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Mammary epithelial-specific disruption of c-Src impairs cell cycle progression and tumorigenesis

The tyrosine kinase c-Src is activated in a large proportion of breast cancers, in which it is thought to play a key role in promoting the malignant phenotype. c-Src activity is also elevated in transgenic mouse models of breast cancer, including the widely used polyomavirus middle-T antigen (PyVmT)...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Marcotte, Richard, Smith, Harvey W., Sanguin-Gendreau, Virginie, McDonough, Rosalie V., Muller, William J.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: National Academy of Sciences 2012
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3286961/
https://ncbi.nlm.nih.gov/pubmed/21628573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1018861108
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