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Mammary epithelial-specific disruption of c-Src impairs cell cycle progression and tumorigenesis
The tyrosine kinase c-Src is activated in a large proportion of breast cancers, in which it is thought to play a key role in promoting the malignant phenotype. c-Src activity is also elevated in transgenic mouse models of breast cancer, including the widely used polyomavirus middle-T antigen (PyVmT)...
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| Main Authors: | , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
2012
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3286961/ https://ncbi.nlm.nih.gov/pubmed/21628573 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1018861108 |
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