MPP8 mediates the interactions between DNA methyltransferase Dnmt3a and H3K9 methyltransferase GLP/G9a

DNA CpG methylation and histone H3 lysine 9 (H3K9) methylation are two major repressive epigenetic modifications, and these methylations are positively correlated with one another in chromatin. Here we show that G9a or G9a-like protein (GLP) dimethylate the amino-terminal lysine 44 (K44) of mouse Dn...

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Huvudupphovsmän: Chang, Yanqi, Sun, Lidong, Kokura, Kenji, Horton, John R., Fukuda, Mikiko, Espejo, Alexsandra, Izumi, Victoria, Koomen, John M., Bedford, Mark T., Zhang, Xing, Shinkai, Yoichi, Fang, Jia, Cheng, Xiaodong
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3286832/
https://ncbi.nlm.nih.gov/pubmed/22086334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms1549
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