Dual role of junctin in the regulation of ryanodine receptors and calcium release in cardiac ventricular myocytes

NON-TECHNICAL SUMMARY: Each heartbeat is accompanied by the coordinated release of calcium ions into cardiac cells through ryanodine receptors, which span the membrane of the sarcoplasmic reticulum. We show that an intra-sarcoplasmic reticulum protein, junctin, interacts with ryanodine receptor chan...

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Bibliographic Details
Main Authors: Altschafl, Beth A, Arvanitis, Demetrios A, Fuentes, Oscar, Yuan, Qunying, Kranias, Evangelia G, Valdivia, Héctor H
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2011
Subjects:
Cardiovascular
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3286686/
https://ncbi.nlm.nih.gov/pubmed/22025663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2011.215988
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