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Stringent integrity requirements for both trans-activation and DNA-binding in a trans-activator, Oct3.

POU-specific and POU-homeo domains of Oct3 were produced in Echerichia coli for characterization of DNA binding to the octamer sequence. POU domain protein including A, B and H domains could bind to the octamer sequence efficiently and specifically, and DNase I footprint analysis gave an indistingui...

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Bibliografiske detaljer
Main Authors: Imagawa, M, Miyamoto, A, Shirakawa, M, Hamada, H, Muramatsu, M
Format: Artigo
Sprog:Inglês
Udgivet: 1991
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC328641/
https://ncbi.nlm.nih.gov/pubmed/1886774
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