Trans-activation and DNA-binding properties of the transcription factor, Sox-18.

Sox-18 is a member of the Sox multi-gene family (Sry-related HMG-box gene). We have bacterially expressed this 378 amino acid protein and demonstrated sequence-specific binding to the Sox DNA-binding motif AACAAAG. A distinct 95 amino acid activation domain was mapped in Sox-18 using GAL4-Sox-18 fus...

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Bibliographic Details
Main Authors: Hosking, B M, Muscat, G E, Koopman, P A, Dowhan, D H, Dunn, T L
Format: Artigo
Language:Inglês
Published: 1995
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC307084/
https://ncbi.nlm.nih.gov/pubmed/7651823
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