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Analysis of herpes simplex virus-induced mRNA destabilizing activity using an in vitro mRNA decay system.

Most host mRNAs are degraded soon after infection of cells with herpes simplex virus type 1 (HSV-1). This early shutoff or early destabilization response is induced by a virion component, the virion host shutoff (vhs) protein. HSV-1 mutants, vhs1 and vhs-delta Sma, which produce defective or inactiv...

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Dettagli Bibliografici
Pubblicato in:Nucleic Acids Res
Autori principali: Sorenson, C M, Hart, P A, Ross, J
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 1991
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC328634/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1653415/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/19.16.4459
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