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Analysis of herpes simplex virus-induced mRNA destabilizing activity using an in vitro mRNA decay system.
Most host mRNAs are degraded soon after infection of cells with herpes simplex virus type 1 (HSV-1). This early shutoff or early destabilization response is induced by a virion component, the virion host shutoff (vhs) protein. HSV-1 mutants, vhs1 and vhs-delta Sma, which produce defective or inactiv...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
1991
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC328634/ https://ncbi.nlm.nih.gov/pubmed/1653415 |
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