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Defining Substrate and Blocker Activity of Alanine-Serine-Cysteine Transporter 2 (ASCT2) Ligands with Novel Serine Analogs

The neutral amino acid transporter alanine-serine-cysteine transporter 2 (ASCT2) belongs to the solute carrier 1 (SLC1) family of solute transporters and transports small, neutral amino acids across the membrane, including the physiologically important and ubiquitous amino acid glutamine. Our unders...

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Autors principals: Albers, Thomas, Marsiglia, William, Thomas, Taniya, Gameiro, Armanda, Grewer, Christof
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Pharmacology and Experimental Therapeutics 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3286296/
https://ncbi.nlm.nih.gov/pubmed/22113081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.111.075648
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