Solid-phase synthesis of DNA fragments containing the modified base 7-hydro-8-oxo-2'-deoxyguanosine.

The 5'-(4,4'-dimethoxytrityl) protected 3'-(2-cyanoethoxy)-N,N-diisopropylphosphoramidite of 7-hydro-8-oxo-2'-deoxy-guanosine, the exocyclic amino and lactam functions of which are protected with acetyl and diphenylcarbamoyl groups, respectively, has been prepared from the 8-brom...

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Detalhes bibliográficos
Main Authors: Roelen, H C, Saris, C P, Brugghe, H F, van den Elst, H, Westra, J G, van der Marel, G A, van Boom, J H
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC328621/
https://ncbi.nlm.nih.gov/pubmed/1886763
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