KLF9 is a novel transcriptional regulator of bortezomib- and LBH589-induced apoptosis in multiple myeloma cells

Bortezomib, a therapeutic agent for multiple myeloma (MM) and mantle cell lymphoma, suppresses proteosomal degradation leading to substantial changes in cellular transcriptional programs and ultimately resulting in apoptosis. Transcriptional regulators required for bortezomib-induced apoptosis in MM...

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Hlavní autoři: Mannava, Sudha, Zhuang, DaZhong, Nair, Jayakumar R., Bansal, Rajat, Wawrzyniak, Joseph A., Zucker, Shoshanna N., Fink, Emily E., Moparthy, Kalyana C., Hu, Qiang, Liu, Song, Boise, Lawrence H., Lee, Kelvin P., Nikiforov, Mikhail A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2012
Témata:
Lymphoid Neoplasia
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3286209/
https://ncbi.nlm.nih.gov/pubmed/22144178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-04-346676
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