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ACE2 overexpression in the paraventricular nucleus attenuates angiotensin II-induced hypertension

AIMS: Angiotensin II (Ang II) has been shown to have both central and peripheral effects in mediating hypertension, for which the hypothalamic paraventricular nucleus (PVN) is an important brain cardio-regulatory centre. Angiotensin-converting enzyme 2 (ACE2) has been identified as a negative regula...

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Bibliografiske detaljer
Main Authors: Sriramula, Srinivas, Cardinale, Jeffrey P., Lazartigues, Eric, Francis, Joseph
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3286198/
https://ncbi.nlm.nih.gov/pubmed/21952934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvr242
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