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An energetically beneficial leader–linker interaction abolishes ligand-binding cooperativity in glycine riboswitches
Comprised of two aptamers connected by a short nucleotide linker, the glycine riboswitch was the first example of naturally occurring RNA elements reported to bind small organic molecules cooperatively. Earlier works have shown binding of glycine to the second aptamer allows tertiary interactions to...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Cold Spring Harbor Laboratory Press
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3285937/ https://ncbi.nlm.nih.gov/pubmed/22279151 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.031286.111 |
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