Sprouty4 Is an Endogenous Negative Modulator of TrkA Signaling and Neuronal Differentiation Induced by NGF

The Sprouty (Spry) family of proteins represents endogenous regulators of downstream signaling pathways induced by receptor tyrosine kinases (RTKs). Using real time PCR, we detect a significant increase in the expression of Spry4 mRNA in response to NGF, indicating that Spry4 could modulate intracel...

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Autori principali: Alsina, Fernando C., Irala, Dolores, Fontanet, Paula A., Hita, Francisco J., Ledda, Fernanda, Paratcha, Gustavo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3285629/
https://ncbi.nlm.nih.gov/pubmed/22384148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032087
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