A P-loop Mutation in Gα Subunits Prevents Transition to the Active State: Implications for G-protein Signaling in Fungal Pathogenesis

Heterotrimeric G-proteins are molecular switches integral to a panoply of different physiological responses that many organisms make to environmental cues. The switch from inactive to active Gαβγ heterotrimer relies on nucleotide cycling by the Gα subunit: exchange of GTP for GDP activates Gα, where...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Bosch, Dustin E., Willard, Francis S., Ramanujam, Ravikrishna, Kimple, Adam J., Willard, Melinda D., Naqvi, Naweed I., Siderovski, David P.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3285607/
https://ncbi.nlm.nih.gov/pubmed/22383884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002553
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados