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Structural Consensus among Antibodies Defines the Antigen Binding Site

The Complementarity Determining Regions (CDRs) of antibodies are assumed to account for the antigen recognition and binding and thus to contain also the antigen binding site. CDRs are typically discerned by searching for regions that are most different, in sequence or in structure, between different...

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Detalhes bibliográficos
Main Authors: Kunik, Vered, Peters, Bjoern, Ofran, Yanay
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3285572/
https://ncbi.nlm.nih.gov/pubmed/22383868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002388
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