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Structural Consensus among Antibodies Defines the Antigen Binding Site
The Complementarity Determining Regions (CDRs) of antibodies are assumed to account for the antigen recognition and binding and thus to contain also the antigen binding site. CDRs are typically discerned by searching for regions that are most different, in sequence or in structure, between different...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Public Library of Science
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3285572/ https://ncbi.nlm.nih.gov/pubmed/22383868 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002388 |
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