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Two sides of the story? Smad4 loss in pancreatic cancer versus head-and-neck cancer
TGFβ signaling Smads (Smad2, 3, and 4) were suspected tumor suppressors soon after their discovery. Nearly two decades of research confirmed this role and revealed other divergent and cancer-specific functions including paradoxical tumor promotion effects. Although Smad4 is the most potent tumor sup...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3285395/ https://ncbi.nlm.nih.gov/pubmed/22321641 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2012.01.054 |
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