Trinucleotide Repeat Containing 6a (Tnrc6a)-mediated MicroRNA Function Is Required for Development of Yolk Sac Endoderm

Tnrc6 family members (Tnrc6a/b/c) are key components of the RNA-induced silencing complex in microRNA (miRNA)-mediated gene suppression. Here, we show that Tnrc6a, also known as GW182, is selectively expressed in the yolk sac endoderm and that gene trap disruption of GW182 leads to growth arrest and...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Jiang, Zhihua, Yu, Nan, Kuang, Pingping, Chen, Melody, Shao, Fengzhi, Martin, Gregory, Chui, David H. K., Cardoso, Wellington V., Ai, Xingbin, Lü, Jining
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3285365/
https://ncbi.nlm.nih.gov/pubmed/22187428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.297937
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados