Assembly and Architecture of Biogenesis of Lysosome-related Organelles Complex-1 (BLOC-1)

BLOC-1 (biogenesis of lysosome-related organelles complex-1) is critical for melanosome biogenesis and has also been implicated in neurological function and disease. We show that BLOC-1 is an elongated complex that contains one copy each of the eight subunits pallidin, Cappuccino, dysbindin, Snapin,...

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Detalhes bibliográficos
Main Authors: Lee, Hyung Ho, Nemecek, Daniel, Schindler, Christina, Smith, William J., Ghirlando, Rodolfo, Steven, Alasdair C., Bonifacino, Juan S., Hurley, James H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Protein Structure and Folding
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3285357/
https://ncbi.nlm.nih.gov/pubmed/22203680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.325746
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